Redermalisation is an innovative method of skin renewal that helps lower the risk of premature ageing. The Xela Rederm range from the Swiss laboratory Hyalual combines hyaluronic acid with sodium succinate, which regulates biochemical processes within cells, supporting regeneration and a more youthful-looking complexion. After the treatment, skin is smoother, brighter and more hydrated.
Redermalisation is an innovative skin renewal method that helps lower the risk of premature ageing. Xela Rederm formulas from the Swiss laboratory Hyalual combine hyaluronic acid with sodium succinate — a substance that regulates biochemical and physiological processes within cells, supporting effective regeneration and a more youthful-looking complexion. It is precisely this sodium succinate (with its antioxidant, redox action) that sets redermalisation apart from classic mesotherapy.
After the treatment, skin is noticeably smoother, brighter and more hydrated. Redermalisation is used on the face, neck, décolletage, hands and the eye area. The formula is administered using the mesotherapy technique, with results visible straight after the treatment. Xela Rederm comes in three versions with different concentrations of active substances, chosen individually to suit the patient's needs and age.
Xela Rederm is a redermalisation treatment — hyaluronic acid combined with sodium succinate, whose antioxidant (redox) action sets it apart from classic hydrating mesotherapies. If your main concern is hydration and biostimulation, take a look at Neauvia Hydro Deluxe (HA + calcium hydroxyapatite). If you are looking for a multi-component nourishing cocktail, check out CytoCare 532 (HA + 55 ingredients).
You will find general information about the administration method on the facial needle mesotherapy page. For established pigmentation and melasma, we run a separate pigmentation therapy — the Cosmelan protocol. The choice of concentration is made by our specialist.
Source: Versum and Booksy reports, as of 30 June 2026. Data for the Xela Rederm Redermalisation treatment (approximate matching). Excludes revenue data.
Binds water within the skin, providing hydration, a denser-looking texture and improved elasticity and firmness.
Regulates biochemical processes within cells, has an antioxidant action and supports regeneration — the hallmark of redermalisation.
Versions 1.1, 1.8 and 2.2 are chosen to suit age and skin needs — from prevention through to advanced signs of ageing.
The formula is administered using the mesotherapy technique; results are visible straight after the treatment. The sodium succinate concentration (16 mg/ml) is fixed, while the hyaluronic acid content varies — the choice of version is made by our specialist.
We use this treatment for 2 indications. It works a little differently for each — below we describe exactly what it does in each case.
Hyaluronic acid combined with sodium succinate hydrates while also providing an antioxidant action. Valued for this delicate area because it improves skin quality with a minimal risk of adding unwanted volume.
02Hyaluronic acid with sodium succinate combines hydration with an antioxidant action. This second component matters for smokers, people with a history of prolonged sun exposure, or those living in the city — wherever skin is under greater oxidative stress.
Not sure which indication matches your situation? See all indications or ask during your consultation.
All treatments are performed with the Xela Rederm formula in one of three versions with different hyaluronic acid concentrations (sodium succinate: 16 mg/ml). The concentration is chosen individually by our specialist.
The publications below relate to hyaluronic acid — the main ingredient of the formula — and its role in hydration, improving skin quality and rejuvenating the eye area.
This study evaluated the efficacy and safety of injectable, non-cross-linked hyaluronic acid for photoageing of the eye area and lateral canthal wrinkles.
Osuna Arellano et al., Clin Cosmet Investig Dermatol 2026 · PubMed →A randomised multicentre trial found that a biorevitalising hyaluronic acid formula improves superficial wrinkles and skin quality.
Fanian et al., J Dermatolog Treat 2023 · PubMed →This clinical study evaluated an injectable anti-ageing complex based on non-cross-linked hyaluronic acid for its efficacy and tolerability in improving skin.
Scarano et al., J Biol Regul Homeost Agents 2021 · PubMed →The cited studies relate to hyaluronic acid — the main ingredient of the formula — not the specific product. The number of treatments is determined by our specialist; results vary between individuals.
The treatment is preceded by a consultation, during which our specialist chooses the formula concentration to suit age and skin needs. Redermalisation is administered using the mesotherapy technique — a series of small injections on the face, neck, décolletage, hands or the eye area. Results are visible straight after the treatment.
Skin assessment and choice of version 1.1, 1.8 or 2.2.
Make-up removal and preparation for injections.
Administration of the formula using the mesotherapy technique in the indicated areas.
Soothing the skin and guidance on post-treatment care.
The treatment is minimally invasive and usually requires no downtime, though the injection sites need gentle care for a few days. A full course is usually 1–4 treatments, determined by our specialist.
For 1–2 days, avoid touching or irritating the injection sites; avoid make-up.
Use a high SPF and avoid sun exposure and sunbeds for a few days.
For 1–2 days, avoid the sauna, swimming pool and intensive training.
Slight redness and minor bruising resolve within a few days.
The best renewal results come from a full course of treatments matched to your skin's age.
Educational and informational material. Detailed advice is provided by our specialist; results and the course of treatment vary between individuals.
Authentic photos from our Velvet Skin Clinic locations in Warsaw (Świętokrzyska — City Centre, Niepodległości — Mokotów).


The price depends on the chosen concentration, the area treated and the number of treatments in the course. A full course is usually 1–4 treatments; we agree the plan and choice of version during your consultation.
"I recommend it. I come regularly for needle mesotherapy treatments. My skin is in much better condition." (translated from Polish)
Natalia Ławniczak · 2025Google review"Nucleofill significantly improved my skin's firmness. I feel so much younger and more confident." (translated from Polish)
Paulina Michalska · 2023Google review"Needle-free mesotherapy was new to me, but I already know I'll be back. My skin looks much better, and the treatment itself was very relaxing. Friendly and competent staff, and a clean, well-kept space." (translated from Polish)
Magda Brodnicka · 2025Google reviewOur specialist assesses every case individually during the consultation interview. The main contraindications are:
Xela Rederm redermalisation is a skin renewal method using Hyalual formulas that combine hyaluronic acid with sodium succinate. Hyaluronic acid hydrates and gives skin a denser-looking texture, while sodium succinate has an antioxidant (redox) action that supports cell regeneration. Results are visible straight after the treatment.
What sets Xela Rederm apart is sodium succinate with its redox/antioxidant action — hence the name redermalisation. Neauvia Hydro Deluxe is an HA biorevitalisation with calcium hydroxyapatite, while CytoCare 532 is a nourishing cocktail with 55 ingredients. The formula is chosen by our specialist.
The 1.1% version is recommended for people aged 28–35 for prevention and dry skin; 1.8% from age 35 for comprehensive rejuvenation; 2.2% for advanced signs of ageing and lax tissue. The concentration is chosen individually by our specialist to suit age and skin.
A full course is usually 1–4 treatments, determined by our specialist. Results include a more youthful-looking, regenerated complexion, a denser-looking texture and lifting effect, improved skin tone, reduced wrinkles, and improved lip contour and facial oval.
The treatment is administered using the mesotherapy technique — a series of small injections. It is minimally invasive and well tolerated by most patients; slight redness or minor bruising may occur and resolves within a few days.
The treatment price starts from 700 zł and depends on the chosen concentration, the area treated and the number of treatments. We agree the exact price and treatment plan during your consultation; you will find the full price list on our pricing page.
Aesthetic medicine treatments at Velvet Skin Clinic are performed exclusively by qualified doctors — with relevant medical education, postgraduate studies in aesthetic medicine and clinical experience. Every treatment is preceded by a consultation, during which the doctor tailors the therapy to your needs, indications and natural facial proportions.




00-116 Warsaw · opposite the Palace of Culture and Science
tel. 500 53 30 30
The publications underpinning this offer — with PMID identifiers and an assessment of the strength of evidence.