Mokotów Clinic:
al. Niepodległości 92/98
City Centre Clinic:
ul. Świętokrzyska 30
01 — Aesthetic Medicine · Collagen Stimulator

Poly-L-Lactic Acid — a gradual lifting effect and collagen renewal

One of the most powerful collagen-stimulating treatments available. It rebuilds and thickens the skin discreetly and gradually, restoring its structure, volume and firmness. The effect is natural and develops over time. A physician-administered treatment in central Warsaw.

Book — City CentreBook — MokotówBook a Consultation →
30+ yearsin medicine
Gradual effectnatural, over time
Effect lasting up to 2 yearslong-lasting
2 clinicsCity Centre · Mokotów
02 — The Treatment

Poly-L-Lactic Acid — a powerful collagen stimulator

Poly-L-lactic acid is one of the most powerful collagen-stimulating treatments available. Its action is discreet — because it is gradual — rebuilding and thickening the skin while restoring its structure, volume and firmness. The final effect is very natural and subtle: sagging skin is gradually lifted, the cheeks and nasolabial folds are replenished, and the skin regains radiance and elasticity.

Learn More

Proven for Over 30 Years

Poly-L-lactic acid has been used in medicine for over 30 years, including as a component of dissolvable surgical sutures and implants. It has a well-established safety profile, as it breaks down completely within the human body. More than 150,000 treatments using this substance have been performed since the late 1990s.

What makes this treatment unique is its discreet, gradual action — the effects appear over time, as the skin's own collagen renewal is naturally stimulated. Poly-L-lactic acid gradually, yet effectively and noticeably, restores skin firmness and elasticity, smoothing and toning it.

03 — Poly-L-Lactic Acid in Numbers

Collagen Stimulators at Velvet Skin Clinic

14treatments performed (2023–2026)
9patients
44%return for further treatments
2clinics in central Warsaw

Poly-L-lactic acid is one of our treatments from the collagen-stimulator family — alongside Profhilo, Nucleofill and Sunekos, of which we have performed 515 in total.

Source: Versum and Booksy reports, as of 30 June 2026. Data matching is approximate (based on procedure name).

04 — How the Collagen Stimulator Works

Why Poly-L-Lactic Acid Works Gradually

01

Stimulates Fibroblasts

Poly-L-lactic acid gradually stimulates fibroblasts to produce your own collagen — it is your own skin that rebuilds its structure.

02

The Effect Develops Over Time

Unlike a filler, it does not provide volume „right away” — the result builds up over weeks as collagen synthesis progresses.

03

Natural and Subtle

A gradual lift of sagging skin, replenishment of the cheeks and nasolabial folds, and a return of radiance and elasticity.

Poly-L-lactic acid breaks down completely in the body — leaving behind only newly produced, natural collagen of the patient's own.

05 — Indications

When It's Worth Having a Poly-L-Lactic Acid Treatment

Poly-L-lactic acid is used to add volume to thin, sagging skin and to lift and strengthen the lower part of the face — particularly when the following are needed:

restoring lost facial contour and firmnesscounteracting skin laxityreducing and smoothing wrinklesimproving skin quality and appearancenourishing skin cellshydrating and stimulating the skinimproving skin firmness and conditionadding volume to the lower face
What We Help With

What Poly-L-Lactic Acid Helps With

We use this treatment for a single indication. Below we describe exactly what it does in this case.

01

Static Wrinkles

Poly-L-lactic acid works most slowly of all the options — and that's its advantage: volume is rebuilt by your own collagen, so the change is gradual and hard to notice from the outside. It requires patience and a series of treatments; you won't see the effect after a single visit.

Read More About This Indication →

Not sure which indication matches your situation? See All Indications or ask during a consultation.

07 — Consultation

Want to Rebuild Your Skin With Your Own Collagen Instead of a Filler? Book a Consultation.

Book a Consultation
08 — Scientific Research

What the Research Says About Poly-L-Lactic Acid

Poly-L-lactic acid (PLLA) is one of the best-documented collagen biostimulators. The studies below relate to PLLA technology — the mechanism shared by poly-L-lactic-acid-based treatments.

PLLA
Collagen I and III

Collagen Synthesis

A comparative study of biostimulators found that poly-L-lactic acid increases the biosynthesis of type I and III collagen — key proteins responsible for skin structure.

Study on PLLA/PDO biostimulators, 2024. PubMed Central →
PLLA
TGF-β/Smad

Molecular Mechanism

In cultured human skin fibroblasts, PLLA increased collagen gene expression and synthesis via the TGF-β/Smad signalling pathway.

In vitro study, 2023. PubMed →
PLLA
in vitro/in vivo

Collagen Synthesis

A study assessing the effect of HA and PLLA fillers on collagen synthesis confirmed PLLA's ability to induce neocollagenesis in in vitro and in vivo models.

Comparative study, 2020. PubMed →

The cited studies relate to poly-L-lactic acid (PLLA) technology, not a specific product brand. The number of treatments and the pace of results are determined individually by the physician; outcomes may vary depending on skin condition.

09 — Procedure and Full Therapy

What a Poly-L-Lactic Acid Treatment Looks Like

This is a minimally invasive lifting treatment, performed by a physician and preceded by a detailed health interview. A local anaesthetic is applied immediately before the treatment. The product is injected deep under the skin in areas where volume loss has been identified. The treatment takes around 30–60 minutes, and the effects last up to 2 years. Patients can return to daily activities immediately afterwards; for a few days, mild discomfort, redness or swelling may occur at the injection site, which resolve on their own.

Health Interview

The physician rules out contraindications and plans the injection areas.

Anaesthesia

Local anaesthesia for treatment comfort.

Product Injection

Deep under the skin, in areas of volume loss.

A Series of 2–4 Treatments

Roughly every 6 weeks; the effect builds up and lasts up to 2 years.

Learn About the Full Therapy

Typically, 2–4 treatments are performed about 6 weeks apart, although the actual number depends on the patient's individual needs and expectations. Because the effect builds up gradually alongside the production of the patient's own collagen, the full result is assessed once the series is complete.

10 — Post-Treatment Care

Aftercare Recommendations — Poly-L-Lactic Acid

The treatment doesn't require downtime, but it's worth taking care of the treated areas in the first few days. Discomfort, redness or swelling may persist at the injection site for a few days — these are temporary reactions.

Massage as Advised by Your Physician

With poly-L-lactic acid, your physician may recommend gently massaging the treated areas — follow their instructions.

Avoid the Sauna and Exercise

Skip the sauna, swimming pool and intense training for 1–2 days.

Protect Your Skin With SPF

Use an SPF cream and avoid intense sun exposure.

Reactions Are Temporary

Discomfort, redness or swelling usually pass within a few days.

Complete the Series

The full effect comes from a series of 2–4 treatments; schedule your follow-up visits with your physician.

This is educational and informational material. Detailed recommendations are provided by your physician during your visit; effects and outcomes vary individually.

11 — Gallery · Clinic and Treatment

See the Clinic and Procedure — Poly-L-Lactic Acid

Authentic photos from our Velvet Skin Clinic locations in Warsaw (Świętokrzyska — City Centre, Niepodległości — Mokotów).

Poly-L-Lactic Acid — Poly-L-Lactic Acid
Poly-L-Lactic Acid
12 — Pricing and Parameters

Poly-L-Lactic Acid — Price in Warsaw

The price is for a single treatment; the full therapy usually involves 2–4 treatments about 6 weeks apart. Poly-L-lactic acid is administered by a physician. The therapy plan is set during your consultation.

Key Parameters

Who Performs It
Aesthetic medicine physician
Duration
30–60 minutes
Number of Treatments
series of 2–4
Price
1,400 zł / treatment
Full Price Listor book a consultation →
13 — Related Therapies and Alternatives

See Also — The Stimulator Family

Instant Volume

Crystalys — Calcium Hydroxylapatite

When you want immediate filling combined with collagen stimulation.

View
Regeneration

Linerase — Atelocollagen

Mesotherapy with ready-made type I collagen — regeneration, scars and stretch marks.

View
Programme

5-Step Collagen Boost

A comprehensive skin-renewal therapy combining collagen stimulation.

View
14 — Patient Reviews

They Trusted Us

★★★★★

„Tissue stimulators are the best treatment. I recommend Velvet Skin Clinic, the best of the best" (translated from Polish)

Karolina Gołda · 2025Google review
★★★★★

„A great treatment, but it matters who performs it. In the hands of Dr Ewelina, the results are amazing" (translated from Polish)

Iwona · 2025Booksy review
★★★★★

„Tissue stimulators improved the oval shape of my face." (translated from Polish)

Maria Borowczyk · 2025Google review
15 — Safety

Contraindications for the Treatment

Each case is assessed individually by the physician during the health interview. The main contraindications are:

pregnancy and breastfeeding
allergy to the product used
active herpes
viral, fungal or bacterial infections and inflammatory skin conditions
blood clotting disorders, blood-thinning medication
uncontrolled diabetes
a tendency to form hypertrophic scars
cancer and autoimmune diseases
16 — Questions and Answers

Frequently Asked Questions — Poly-L-Lactic Acid

What is poly-L-lactic acid (PLLA)?

Poly-L-lactic acid is one of the most powerful collagen stimulators, used in medicine for over 30 years, including in surgical sutures and implants. It breaks down completely in the body while stimulating the skin to produce its own collagen — leaving behind only new, natural tissue.

How does poly-L-lactic acid differ from a filler?

A filler provides volume immediately, supplementing the tissue with the product. Poly-L-lactic acid works differently: it doesn't fill instantly, but gradually stimulates the skin to produce its own collagen. The effect is more natural and develops over weeks, providing a gradual lifting and rebuilding effect.

When do the effects of poly-L-lactic acid become visible?

The effects appear gradually, as the skin produces new collagen — usually over several weeks after successive treatments. The full result is assessed once the series of 2–4 treatments is complete. The pace depends on the individual condition of the skin.

How many poly-L-lactic acid treatments are needed?

Typically, 2–4 treatments are performed about 6 weeks apart. The actual number depends on the patient's individual needs and expectations, as well as the initial condition of the skin. The physician sets the therapy plan during the consultation. The effect lasts up to 2 years.

Does a poly-L-lactic acid treatment hurt?

A local anaesthetic is applied immediately before the treatment, so discomfort is minimal. For a few days after the treatment, redness, swelling or a feeling of discomfort may occur at the injection site — these are temporary reactions that resolve on their own.

How much does a poly-L-lactic acid treatment cost?

The price of a single treatment is 1,400 zł. The full therapy usually involves 2–4 treatments, so the total cost depends on the plan agreed with your physician. You'll find the full price list on the pricing page, and you can book a consultation online or by phone.

17 — Who Performs the Treatments

Injectable Treatments Are Performed by Our Physicians

Aesthetic medicine treatments at Velvet Skin Clinic are performed exclusively by qualified physicians — with relevant medical education, postgraduate studies in aesthetic medicine, and clinical experience. Every treatment is preceded by a consultation, during which the physician tailors the therapy to your needs, indications and natural facial proportions.

Dr Bartłomiej Kurczab — aesthetic medicine physician, Velvet Skin Clinic
Dr Bartłomiej Kurczabaesthetic medicine physicianAesthetic medicine, maxillofacial surgery
Dr Michał Łata — aesthetic medicine physician, Velvet Skin Clinic
Dr Michał Łataaesthetic medicine physicianAesthetic and anti-ageing medicine, regenerative medicine, longevity
Dr Anna Sancewicz — aesthetic medicine physician, Velvet Skin Clinic
Dr Anna Sancewiczaesthetic medicine physicianAesthetic medicine
Dr Anna Kowalczyk — aesthetic medicine physician, Velvet Skin Clinic
Dr Anna Kowalczykaesthetic medicine physicianAesthetic and anti-ageing medicine, combination therapies, anti-ageing prevention

Meet the Full Velvet Skin Clinic Medical Team →

18 — Booking

Book Your Treatment — Poly-L-Lactic Acid

City Centre Clinic

ul. Świętokrzyska 30

00-116 Warsaw · opposite the Palace of Culture and Science
Phone 500 53 30 30

Book OnlineCall
Mokotów Clinic

al. Niepodległości 92/98

02-585 Warsaw · the heart of Mokotów
Phone 500 53 30 55

Book OnlineCall
VELVET SKIN CLINIC · aesthetic medicine and laser therapy · velvetskin.pl
recepcja@velvetskin.pl
City CentreMokotów
Scientific Evidence

See What the Research Says

The publications underpinning this treatment — with PMID identifiers and an assessment of evidence strength.

AtelocollagenOral Collagen vs StimulatorsPoly-L-Lactic AcidTissue StimulatorsFull Knowledge Base
PL
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VELVET SKIN CLINIC - ŚRÓDMIEŚCIE
ul. Świętokrzyska 30
00-116 Warszawa
Tel. + 48 500 53 30 30
VELVET SKIN CLINIC - MOKOTÓW
al. Niepodległości 92/98
02-585 Warszawa
Tel. +48 500 53 30 55

Email: recepcja@velvetskin.pl
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