Mokotów Clinic:
al. Niepodległości 92/98
City Centre Clinic:
ul. Świętokrzyska 30
01 — Aesthetic Medicine · Atelocollagen Mesotherapy

Linerase™ — next-generation atelocollagen

A bioactive type I atelocollagen for intensive skin regeneration and repair. It restores firmness and density, smooths wrinkles, and supports the treatment of atrophic and post-acne scars and stretch marks. Mesotherapy for the face, neck, décolletage, hands and the whole body.

Book — City CentreBook — MokotówBook a consultation →
Type I collagenready-to-use, bioactive
Scars and stretch markstissue regeneration
129 treatmentsat our clinics
2 clinicsCity Centre · Mokotów
02 — About the treatment

Linerase — type I atelocollagen for mesotherapy

Linerase™ is a bioactive atelocollagen preparation used for intensive skin regeneration and repair, restoring its firmness and density, smoothing wrinkles, and treating post-acne and atrophic scars as well as reducing stretch marks. Linerase atelocollagen stimulates the production of new fibroblasts responsible for generating endogenous collagen and elastin in the skin, supporting its proper condition: firmness, thickness and elasticity.

See the details

Biocompatible next-generation collagen

Linerase is a type I atelocollagen — a bioactive mesotherapy preparation that regenerates and rebuilds the skin, restoring its firmness and radiance. It is designed to stimulate fibroblasts to produce endogenous collagen fibres as new tissue filling. It increases the number of fibroblasts responsible for producing endogenous collagen in the skin, reduces sagging, stretch marks and atrophic scars, and smooths wrinkles.

Linerase does not irritate the skin, does not trigger allergic reactions, and is not cytotoxic. It is a biodegradable, biocompatible material that dissolves spontaneously and completely in the skin.

03 — Linerase in numbers

The Velvet Skin Clinic experience

130Linerase treatments performed (2021–2026)
68patients
52%return for further treatments
2clinics in central Warsaw

Linerase is one of our flagship atelocollagen skin regeneration treatments — we have been performing it since 2021.

Source: Versum and Booksy reports, as of 30 June 2026. Data matching is approximate (based on procedure name).

04 — Type I atelocollagen — how it works

Why Linerase regenerates the skin

01

Ready-to-use type I collagen

Linerase delivers bioactive, ready-to-use type I collagen to the skin — unlike stimulators, which only trigger its synthesis.

02

Stimulates fibroblasts

It increases the number and activity of fibroblasts that produce endogenous collagen and elastin — the tissue rebuilds itself from the ground up.

03

Biocompatible and gentle

It does not irritate the skin, is not cytotoxic, and does not trigger allergic reactions; it dissolves completely in the skin.

Through the reconstruction of connective tissue, Linerase rebuilds and regenerates the skin of the face, neck, décolletage, hands and the whole body, restoring its natural elasticity.

05 — Indications

When to consider Linerase mesotherapy

Linerase can also be used preventively — to slow down the ageing process by maintaining proper collagen levels. Main indications:

visible signs of ageing: wrinkles, loss of facial contourbiorevitalisation of the face, neck, décolletage, hands and the whole bodyatrophic and post-acne scarsstretch mark treatmenttired, dehydrated skin in need of regenerationskin that has lost firmness and elasticity

Looking to reduce scars or stretch marks with a laser-based method? Also see laser scar removal and laser stretch mark removal — during your consultation, we will match the method to your skin.

What we help with

What Linerase helps with

We use this treatment for one specific indication. Below we describe exactly how it works in that case.

01

Static wrinkles

Atelocollagen is ready-made collagen delivered directly into the skin, rather than a substance that merely triggers its production. We choose Linerase when the skin has lost its own scaffolding and needs rebuilding material, not another stimulus.

Read more about this indication →

Not sure which indication matches your situation? See all indications or ask us during your consultation.

07 — Consultation

Scars, stretch marks, or loss of firmness? Book a free consultation and skin assessment for Linerase mesotherapy.

Book a consultation
08 — Scientific research

What research says about injectable collagen

Injectable collagen preparations are the subject of peer-reviewed publications evaluating their efficacy and safety. The studies below relate to the class of collagen preparations — a mechanism shared with atelocollagen.

Collagen
Review

Efficacy and safety

A current clinical review of injectable collagen preparations in aesthetic and regenerative medicine summarises their efficacy and favourable safety profile.

Clinical review, 2023. PubMed Central →
Collagen
Review

Effect on the skin

A review of clinical studies on collagen therapy indicates improved skin integrity, reduced wrinkles, and support for skin rejuvenation processes.

Review of clinical studies, 2021. PubMed Central →
Mesotherapy
Histology

Skin rejuvenation

A histological and immunohistochemical evaluation of mesotherapy in facial rejuvenation examines the effect of intradermal injections on skin structure and quality.

Histological study, 2012. PubMed Central →

The cited publications relate to the class of injectable collagen preparations and mesotherapy in general, not to a specific product brand. The number and spacing of treatments are determined individually; results may vary depending on skin condition.

09 — Procedure and full course of therapy

What a Linerase treatment looks like

The treatment requires no special preparation. First, a health interview is carried out to rule out any contraindications. The skin is then numbed with a specialist anaesthetic cream, and after around 30 minutes the preparation is administered subcutaneously using the mesotherapy technique. Immediately after the treatment, redness, stinging, swelling or tenderness may appear at the injection site — these symptoms usually resolve on their own within a matter of minutes, and in exceptional cases within a few days. Patients can return to their daily activities straight after the treatment.

Health interview

Ruling out contraindications and assessing skin condition.

Numbing

Specialist anaesthetic cream; a wait of around 30 minutes.

Mesotherapy

Subcutaneous administration of atelocollagen using the mesotherapy technique.

Course of 2–4 treatments

Every 2 weeks; one maintenance treatment after a year.

Learn more about the full course of therapy

A full course of therapy consists of 2–4 treatments carried out at two-week intervals — depending on recommendations and the patient’s skin condition. After a year, one maintenance treatment is recommended to sustain the regenerative effect.

10 — Post-treatment care

Post-treatment recommendations — Linerase

The treatment requires no recovery time. Immediately afterwards, redness, stinging, swelling or tenderness may appear at the injection site — these are temporary reactions that usually resolve within a matter of minutes.

Avoid irritating the skin

On the first day, avoid heavy make-up and harsh cosmetics around the injection sites.

Avoid saunas and exercise

Skip the sauna, swimming pool and intense training for 1–2 days.

Protect your skin with SPF

Use an SPF cream and avoid intense sun exposure.

Reactions are temporary

Redness or swelling usually pass within minutes, and less often within a few days.

Complete the course

The full effect comes from a course of 2–4 treatments every 2 weeks, with a maintenance treatment after a year.

This material is for information and educational purposes. Detailed recommendations are provided by the practitioner performing the treatment; results and recovery vary individually.

11 — Gallery · Clinic and treatment

See the clinic and the procedure — Linerase

Authentic photos from our Velvet Skin Clinic locations in Warsaw (Świętokrzyska — City Centre, Niepodległości — Mokotów).

Linerase™ — Linerase treatment procedure
Linerase treatment procedure
12 — Pricing and key facts

Linerase — price in Warsaw

The price is for a single treatment; a full course usually includes 2–4 treatments at two-week intervals, followed by a maintenance treatment after a year. We agree the treatment plan during your consultation.

Key facts

Who performs it
Doctor or cosmetologist
Duration
30–60 minutes
Number of treatments
course of 2–4
Price
1400 zł / treatment
Full price listor book a consultation →
13 — Related therapies and alternatives

See also — the collagen and regeneration family

Collagen stimulation

Poly-L-lactic acid

When you want a gradual boost to your own collagen production and a lift that builds over time.

See
Instant volume

Crystalys — calcium hydroxyapatite

When you need immediate volume and contouring of the facial oval.

See
Biorevitalisation

Nucleofill — polynucleotides

Biostimulation and DNA-level skin regeneration — combines well with atelocollagen.

See
14 — Patient reviews

They trusted us

★★★★★

„Tissue stimulators are the best treatment. I recommend Velvet Skin Clinic, the best of the best” (translated from Polish)

Karolina Gołda · 2025Google review
★★★★★

„Great treatment, but it really matters who performs it. In Dr Ewelina’s hands, the results are fantastic” (translated from Polish)

Iwona · 2025Booksy review
★★★★★

„Tissue stimulators improved the contour of my face.” (translated from Polish)

Maria Borowczyk · 2025Google review
15 — Safety

Contraindications for the treatment

The practitioner assesses each case individually during the health interview. Main contraindications:

pregnancy and breastfeeding
allergy to the preparation used
active cold sores (herpes)
hypersensitivity to hyaluronic acid
viral, fungal or bacterial infections and inflammatory skin conditions
blood clotting disorders, blood-thinning medication
uncontrolled diabetes
tendency to hypertrophic scarring
cancer and autoimmune diseases
previous permanent fillers (e.g. Aquamid)
16 — Questions and answers

Frequently asked questions — Linerase

What is Linerase atelocollagen?

Linerase is a bioactive type I atelocollagen for mesotherapy. It delivers ready-made collagen to the skin and stimulates fibroblasts to produce endogenous collagen and elastin. It is biocompatible and biodegradable — it does not irritate the skin, is not cytotoxic, and dissolves completely in the skin.

How does Linerase differ from collagen stimulators?

Stimulators, such as poly-L-lactic acid or calcium hydroxyapatite, only trigger the skin’s own collagen production. Linerase delivers ready-made type I collagen via mesotherapy while also activating fibroblasts. This makes it a regenerative treatment, particularly for atrophic scars and stretch marks.

Does Linerase help with scars and stretch marks?

Yes. Linerase is indicated for the treatment of atrophic and post-acne scars and for reducing stretch marks, through the reconstruction of connective tissue and collagen. For scars and stretch marks, the doctor may also suggest laser-based methods; we determine the best approach during your consultation.

Which areas of the body can Linerase be used on?

Linerase rebuilds and regenerates the skin of the face, neck, décolletage, hands and the whole body. Through the reconstruction of connective tissue, it restores natural elasticity in areas prone to sagging, stretch marks and loss of firmness.

How many Linerase treatments are needed?

A full course of therapy usually consists of 2–4 treatments carried out at two-week intervals, depending on skin condition and recommendations. After a year, one maintenance treatment is recommended to sustain the regenerative effect.

How much does a Linerase treatment cost?

A single treatment costs 1400 zł. A full course usually includes 2–4 treatments, so the total cost depends on the plan agreed during your consultation. You will find the full price list on our pricing page, and you can book a consultation online or by phone.

17 — Who performs the treatments

Injectable treatments are performed by our doctors

Aesthetic medicine treatments at Velvet Skin Clinic are performed exclusively by qualified doctors — with relevant medical training, postgraduate studies in aesthetic medicine, and clinical experience. Every treatment is preceded by a consultation, during which the doctor tailors the therapy to your needs, indications and natural facial proportions.

Dr Bartłomiej Kurczab — aesthetic medicine doctor, Velvet Skin Clinic
Dr Bartłomiej Kurczabaesthetic medicine doctorAesthetic medicine, maxillofacial surgery
Dr Michał Łata — aesthetic medicine doctor, Velvet Skin Clinic
Dr Michał Łataaesthetic medicine doctorAesthetic and anti-ageing medicine, regenerative medicine, longevity
Dr Anna Sancewicz — aesthetic medicine doctor, Velvet Skin Clinic
Dr Anna Sancewiczaesthetic medicine doctorAesthetic medicine
Dr Anna Kowalczyk — aesthetic medicine doctor, Velvet Skin Clinic
Dr Anna Kowalczykaesthetic medicine doctorAesthetic and anti-ageing medicine, combination therapies, anti-ageing prevention

Meet the full Velvet Skin Clinic medical team →

18 — Booking

Book your treatment — Linerase

City Centre Clinic

ul. Świętokrzyska 30

00-116 Warsaw · opposite the Palace of Culture and Science
tel. 500 53 30 30

Book onlineCall
Mokotów Clinic

al. Niepodległości 92/98

02-585 Warsaw · the heart of Mokotów
tel. 500 53 30 55

Book onlineCall
VELVET SKIN CLINIC · aesthetic medicine and laser therapy · velvetskin.pl
recepcja@velvetskin.pl
City CentreMokotów
Scientific evidence

See what the research says

The publications underpinning this treatment — with PMID identifiers and an evidence strength rating.

AtelocollagenFull Knowledge Base
PL
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VELVET SKIN CLINIC - ŚRÓDMIEŚCIE
ul. Świętokrzyska 30
00-116 Warszawa
Tel. + 48 500 53 30 30
VELVET SKIN CLINIC - MOKOTÓW
al. Niepodległości 92/98
02-585 Warszawa
Tel. +48 500 53 30 55

Email: recepcja@velvetskin.pl
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